CD274 and glioblastoma: Interestingly, several of those genes had been previously described to be overexpressed and implicated in GBM tumorigenesis, including: CA9 (carbonic anhydrase 9) (Boyd et al., 2017), PDL1 (Programmed Death Ligand 1, also known as CD274) (Jacobs et al., 2009), and IL13RA2 (Interleukin 13 Receptor Subunit Alpha 2).