PBRM1 and nonpapillary renal cell carcinoma: As shown in Figure 1A, in bladder urothelial carcinoma (BLCA), breast invasive carcinoma (BRCA), colon adenocarcinoma (COAD), lung adenocarcinoma (LUAD), kidney renal clear cell carcinoma (KIRC, ccRCC), kidney renal papillary cell carcinoma (KIRP) tumors, there was a significant decrease in the expression level of PBRM1 RNA in cancers compared with normal tissues.