The results showed that the microenvironments containing OMD and OMD+rhBMP-7 significantly upregulated ALP (P < 0.001), OCN (P < 0.001), and BMP-2 (P < 0.01) mRNA expressions in hUC-MSCs on days 7 and 14. The gene discussed is BMP2; the disease is occult macular dystrophy.