While a number of PTVs were detected in these genes, two splicing mutations, CEACAM6 c.∗40 + 2T > G and CEACAM8 c.∗40 + 2T > G, were individually determined to be associated with European American breast cancer, both of which affect non-coding exons in the 3′ UTR. Here, CEACAM6 is linked to breast carcinoma.