The frequency of Mtb-specific CD8 T cells was similar among TBI-IMID (Figures 3A, B), TBI subjects (Figures 3C, D), and active-TB (Figures 3E, F) patients at T0 and T1 and the responders produced mainly IFN-γ in response to TB1 or TB2 stimulations. Here, REEP5 is linked to tuberculosis.