Roche et al. (2008) and Guerin-Dubourg et al. (2012) described albumin as an antioxidant, and it might be elevated in our animals to compensate the higher levels of reactive oxygen species (ROS) induced by diabetes (Raza et al., 2011; Patche et al., 2017; Sinzato et al., 2019) and obesity (Diniz et al., 2004; Burneiko et al., 2006; De Sibio et al., 2013). The gene discussed is ALB; the disease is obesity due to melanocortin 4 receptor deficiency.