In the rat model of postherpetic neuralgia, THSWD has an analgesic effect on postherpetic neuralgia in rats by inhibiting the release of inflammatory factors such as tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) and reducing the apoptosis of spinal nerve cells (Xu et al., 2021). Here, TNF is linked to neuralgia.