The fact that no hyperinsulinism and insulin resistance were observed as a result from exposure to high-intensity infrasound and from increased plasma corticosterone levels could point to a delayed response to this stressor and we argue that a longer period of exposure would be needed to observe changes in insulin production, insulin resistance and glucose tolerance25, as seen in type 2 diabetes mellitus pathophysiology26. Here, INS is linked to type 2 diabetes mellitus.