Regarding cancer drivers, we identified to CDKN1A, ERBB2, FLNA, MTOR, NF1, NFE2L2, SDC4, SMAD4, MYH9, NOTCH2, PTEN, GNA13, HIF1A, NACA, and GNAS as significantly expressed genes. The gene discussed is CDKN1A; the disease is cancer.