Pretreatment with eTAT-Ppm1b provided even greater suppression of TNF-induced necroptosis than the positive control, in which Ppm1b was overexpressed through lentivirus infection (Lenti-Ppm1b); however, almost no suppression was observed in the T-Ppm1b- or Ppm1b-pretreated groups compared the negative control (PBS). The gene discussed is PPM1B; the disease is lentivirus infection.