As shown in Supplementary Fig. 2d, e, and Supplementary Table 1, major immune cell types in cancers including CD4+ T, CD8+ T, Treg, NK, monocyte, macrophages, neutrophil, B, plasma B, plasmacytoid dendritic cells (pDCs), and conventional DCs (cDCs). The gene discussed is CD8A; the disease is cancer.