IPA analysis suggested increased AHR signaling in SARS-CoV-2 infected cells (Fig. 2a,b and Supplementary Data 1) together with other pathways previously associated with viral infection, either as part of the host immune response against viruses (interferon signaling27–29, IL-627,30–32 IL-830,31, NF-κB33, Toll-like receptor29,34, unfolded Protein Response35) or as part of a viral strategy to promote replication (PI3K/AKT36). This evidence concerns the gene AHR and viral infectious disease.