A more detailed analysis of 1100 patients with breast cancer (BRCA) revealed significant positive correlations between Il12b, Ifng, Ccl4, Ccl5, Cxcl9, and Cxcl10 gene expression levels and tumor infiltration of CD8+ T cells and M1 macrophages (Fig. 8b). The gene discussed is IFNG; the disease is invasive breast carcinoma.