In contrast, all interrogated genes showed insignificant or negative correlation with tumor infiltration of M2 macrophages across the majority of tumor types, albeit some positive correlation was noted, namely with Ccl3 and Ccl4 in colon adenocarcinoma (COAD), esophageal cancer (ESCA), and HPV‒ head and neck squamous carcinoma (HNSC). The gene discussed is CCL4; the disease is esophageal cancer.