In fact, TMPRSS2 expression on nasal epithelial cells was already found to be higher in Black individuals than in White, Latino, and Asian individuals,222 which could explain the 2–3 times higher incidence of COVID-19 in Black individuals than in other individuals.223 The functional polymorphisms of TMPRSS2 should be studied as a priority to identify patients who could greatly benefit from these protease inhibitors or ADT. Here, TMPRSS2 is linked to COVID-19.