GATA6 and neoplasm: Moreover, compared with the oe-NC + sh-NC group, the cell sphere formation ability, the cell penetrated the membrane, and the tumor volume were decreased, but the sensitivity to gemcitabine was enhanced in the oe-LINC00261 + oe-GATA6 + sh-NC group (p < 0.05), whereas these were all reversed in the oe-LINC00261 + oe-GATA6 + sh-ITIH5 group (p < 0.05) (Fig. 7F–I).