LINC00261 and neoplasm: Moreover, the effect of the overexpression of the LINC00261 on the self-renewal ability, cell invasion, drug resistance, and tumorigenicity of PANC-1 stem cells was assessed by means of cell sphere formation assay (Fig. 3F), Transwell assay (Fig. 3G), cytotoxicity test (Fig. 3H), and tumor xenograft in nude mice (Fig. 3I).