Moreover, compared with the oe-NC + sh-NC group, the cell sphere formation ability, the invasive ability, the resistance to gemcitabine, and the tumor growth were restrained in the oe-LINC00261 + sh-NC group (p < 0.05), while those abilities of PANC-1 stem cells affected by oe-LINC00261 were rescued by sh-GATA6 (p < 0.05) (Fig. 6F–I). Here, GATA6 is linked to neoplasm.