LCN2 and stroke disorder: Lcn2 and Serpina3n were among the most highly upregulated mRNAs in reactive astrocytes following experimental stroke in mice [90], were both upregulated in Müller cells undergoing astrogliosis [62, 91, 92], and were recently identified as being highly upregulated in endothelial cells in a mouse experimental autoimmune uveitis model [93].