Fifteen genes including LTB4R2, HCN4, FZD9, GRIK5, CREB3L4, TACR2, FRMD1, LHB, FGF3, TEAD3, GRIN2D, GNRH2, PRLH, GPR156, and CRHR2 were also determined as potential biomarkers for ATLL. Here, CREB3L4 is linked to adult T-cell leukemia/lymphoma.