MAPK8 and asthma: Several studies have shown that many molecular signaling pathways, such as JAK/STAT/MAPK, NF-κB, Wnt/β-catenin, PI3K/Akt, JNK, Fas/FasL, TLRs/MyD88, and Keap1/Nrf2/ARE, are important in the pathophysiology of asthma [14, 24–28].