Most of the top-10 upregulated proteins had already been reported to play a role in oncogenesis and/or to be positively associated with poor prognosis in various cancers, including NDRG1, PSAT1, COL7A1, SLC25A22 and CD9, classified as cancer-related or disease-related genes in the Human Protein Atlas (http://www.proteinatlas.org/). Here, SLC25A22 is linked to cancer.