For example, Microsomal triglyceride transfer protein (MTTP) rs1800591 increases the development of NALFD by affecting VLDL secretion, while Uncoupled protein 2 (UCP2) rs695366 reduces the progression of NASH through lipid antioxidant activity [20, 21]. The gene discussed is MT-TP; the disease is metabolic dysfunction-associated steatohepatitis.