In addition, multiple tumor immune-related pathways such as Toll Like Receptor Signaling Pathway (ES = 0.713, NOM P = 0.004, FDR q-val = 0.184), Nuclear Signaling by ERBB4 (ES = 0.715, NOM P = 0.006, FDR q-val = 0.186) and Interleukin 6 Family Signaling (ES = 0.701, NOM P = 0.004, FDR q-val = 0.182) were also active in the GBM process. Here, IL6 is linked to neoplasm.