Moreover, the LNPEP gene product plays a pleiotropic role in various biological processes, which are closely associated with the pathogenesis of HT, diabetes, and other metabolic consequences i.e., the glucose uptake action mechanism via the insulin-responsive glucose transporter GLUT4 receptor, vasopressin clearance system, and serum sodium levels regulation [32]. Here, LNPEP is linked to hematocrit.