The gene expression of multiple inflammatory markers in the heart was significantly upregulated in tumor-bearing mice as compared to tumor-free mice, including the pro-inflammatory cytokines IL-1α (Figure 3A), IL-1β (Figure 3B), IL-6 (Figure 3C), and TNF- α (Figure 3D) and the inflammatory chemokines Mcp-1 (Figure 3E), Cxcl1 (Figure 3F), and Cxcl10 (Figure 3H). The gene discussed is TNF; the disease is neoplasm.