CXCL8 and metabolic syndrome: Similar to the pathways enriched in DMRs from the continuous AF-alb model, the DMRs for the recurrent vs. low model were also enriched in nervous system- (particularly the hypomethylated DMRs; e.g., axon guidance and GABA-R receptor II signalling), inflammatory- (particularly the hypomethylated DMRs; e.g., IL8- and CXCR1-mediated signalling) and adipose- (enriched in both hyper- and hypo-methylated DMRs; e.g., genes targeted by miRNAs in adipocytes, visceral fat deposits and metabolic syndrome, eicosanoid biosynthesis, and regulation of fat cell differentiation) related pathways.