Additionally, a positive correlation between the levels of IL-6 and G-CSF and maximal spinal cord lesion length in the relapse phase in NMO/NMOSD patients is observed (IL-6: r = 0.47, p = 0.035; G-CSF: r = 0.47, p = 0.038), while in the remission phase, no significant correlation between clinical parameters and cytokine levels in RRMS or NMO/NMOSD was reported [116]. Here, CSF3 is linked to neuromyelitis optica.