Besides the presence of several molecular mechanisms responsible for the progression of IPF, the molecular driver in IPF progression can be considered TGFβ, which triggers the proliferation, migration and fibroblast favoring of transdifferentiation into myofibroblasts, culminating in the deposition of aberrant extracellular matrix [53]. Here, TGFB1 is linked to idiopathic pulmonary fibrosis.