Suppresses: review, oxidative stress and lipid peroxidation, IL-1ß, TNFα, IL-6, COX-2, NOS-2, NF-kBEnhances: levels of glutathione, catalase, glutathione peroxidase, and glutathione reductaseOthers: D-limonene metabolite; strong candidate for cancer treatments; induce apoptosis to cancer cells; oral treatment cause intestinal side effects; tissue regeneration improved; blocked formalin-, capsaicin-, and glutamate-induced nociceptive behavior. The gene discussed is TNF; the disease is cancer.