Suppresses: in vivo, increased survival rates in mice with myocardial infarction. Suppressed TNFα, IL-1ß, IL-6, monocyte chemoattractant protein 1 (MCP-1) [366]; in vivo and in vitro, inhibits acid-induced inflammation, suppress TNFα, IL-1ß, IL-6 through regulating TRPV1 [367]Receptors/Channels: TRPM8, TRPV1. The gene discussed is TNF; the disease is myocardial infarction.