Immunofluorescence staining on transverse sections with a GFP antibody to stain transfected cells (Figure 1A), co-stained with phalloidin (Figure S1), allowed to highlight that while the neural tube is still morphologically affected (compare to the control/pCIG condition and to the contralateral/non-electroporated part of the neural tube), the extent of neoplasia is much weaker in all the embryos analyzed when MEK1ca is co-transfected with the HOXB8 expressing vector (>10 embryos analyzed for each condition). The gene discussed is HOXB8; the disease is neoplasm.