NELL2 (Figure 3B and Figure S9) (neural EGFL like 2) for example, expressed in the neural tube and involved in neural development [42], has also been described as a tumor suppressor since it is enriched in normal nerve cells compared with nervous system tumors [43] and inhibits cancer cell migration in renal cell carcinoma [44]. This evidence concerns the gene NELL2 and renal cell carcinoma.