Sepsis has now been defined as a dysregulated host response to infection, leading to life-threatening organ dysfunction, and is associated with a strong stimulation of PRRs by PAMPs and DAMPs, leading to the production of proinflammatory cytokines, such as tumor necrosis factor (TNF)-α, IL-1β, IL-6, and IL-8 [3]. This evidence concerns the gene TNF and infection.