Notably, Ogt is overexpressed in many cancers and there is a positive relationship between the Ogt expression level and cancer metastatic progression [56]; therefore, the evaluation of the effects of Ogt inhibition on cell-signaling-targeting drugs such as gefitinib [57] and everolimus [58] in the context of bone metastasis could offer valuable insights that could help in developing promising therapies. This evidence concerns the gene OGT and cancer.