LRG1 and age-related macular degeneration: As shown in Figure 4a, the average concentration of LRG1 was significantly higher in the aqueous humor of nvAMD patients than in controls (baseline AMD mean = 11.46 ± 7.22 ng/mL [range of variation = 0–27.74], controls mean = 7.46 ± 4.83 ng/mL [0–17.27]; p = 0.0011).