Concerning NPC, in symptomatic NPC1nmf164/nmf164 mice they found an increased number of microglia in the hippocampus, cortex, and cerebellum; in the latter, microglia were characterized by an amoeboid morphology and were positive to MBP staining, indicative of accumulation of myelin debris. Here, MBP is linked to nasopharyngeal carcinoma.