ITGAM and myocarditis: Because of the important role of the complement pathway in the pathogenesis of CVB3 myocarditis in male mice [71], and because plastic caging and the EPA reference dose of BPA increased CD11b/CR3 expression in the males with myocarditis (p = 0.002 and p = 0.04, respectively), we examined the expression of complement components and receptors in the heart of mice who were housed in plastic caging or exposed to 250 μg BPA/L in their drinking water.