Likewise, under AZ(−) conditions, THDC increased expression of genes belonging to the STAT1-57 module (P < 0.01), which is a set of genes activated by interferon signaling with elevated expression in inflammatory skin disease (e.g., MX2, IFIT3, IFI44; Figure 5K,L) [53]. This evidence concerns the gene IFIT3 and inflammatory skin disease.