Topical administration of glycerol seems the most likely avenue for its use to treat psoriasis, because it can then act as an emollient, a hydrogen peroxide transport inhibitor and a precursor for the formation of phosphatidylglycerol, although in this study, oral glycerol was used as a tool to determine whether its PLD2-mediated conversion to phosphatidylglycerol was responsible for glycerol’s beneficial effects. The gene discussed is PLD2; the disease is psoriasis.