Since other medications, such as anti-TNFα agents, have possible serious side effects, which include reactivation of latent tuberculosis, increased risk of serious infections and lymphoma, hepatotoxicity and worsening of congestive heart failure [54], our results suggest that glycerol may be useful for the long-term treatment of psoriasis, perhaps in mild psoriasis or after the disease is brought under control using biologicals or other therapies. Here, TNF is linked to congestive heart failure.