Given the overall abundance of myeloid cells in PCa tumors, myeloid cells were reclassified as shown in Figure 2B. Cluster 0 cells were positive for Cd68, Cd49/Adgre1, Cx3cr1, Cd11c/Itgax, and Cxcl16 and negative for Ccr2 and Cd62l/Sell, suggesting that these cells were non-classical monocytes committed to an M2 phenotype. Here, ADGRE1 is linked to posterior cortical atrophy.