With the data given in Figure 3 of [46], we estimate the difference of the groups to be between 1500 and 2500 CD8+ T cells per mm2, equaling 5.8–12.5 × 104 cells/mm3 or 3–6.5 × 107 cells in a 1 cm diameter circular tumor, assuming homogenous cell distribution. The gene discussed is CD8A; the disease is neoplasm.