Other factors that were altered by FH in RPE cells in our study include CXCL1/GROα, a chemokine responsible for neutrophil recruitment and activation [54] that has been found increased in aqueous humor of AMD patients [55]; and MIP-1α, as well as MIP-1β, factors involved in inflammation-mediated damage in the retina [56]. Here, CXCL1 is linked to age-related macular degeneration.