TMPRSS2 inhibition is a safe and efficient treatment of viral infections (MERS-CoV, SARS-CoV, SARS-CoV-2, several H1N1 subtypes of influenza A viruses, and Asian H7N9 influenza virus) that utilize TMPRSS2 for implantation in host cells [148,149,150]. Here, TMPRSS2 is linked to viral infectious disease.