DM1 myotubes show decreased levels of lumican (LUM), which belongs to the SLRP family and has similar functions to DCN. In both myoblasts and myotubes, collagens, cadherines and protocadherines are upregulated, while elastin (ELN) is strongly upregulated in myotubes only (log2FC = 3.4). Here, LUM is linked to myotonic dystrophy type 1.