Therefore, it was important to examine the effect of DOPA and cyclen-based compounds modified by conjugated amino acid residues on the amyloid self-assembly of the pro-inflammatory protein S100A9, which has been shown to be a central component of the amyloid neuro-inflammatory cascade in Alzheimer’s, Parkinson’s, and traumatic brain injury [11,12,13]. The gene discussed is S100A9; the disease is Parkinson disease.