Expectedly, FBXO28 is overexpressed in several tumor types, including breast, ovarian, testicular, and neuronal cancers, while immunohistochemical studies of tumor microarrays confirmed that phosphorylated FBXO28 was frequently overexpressed and associated with larger, more advanced tumors and poor survival in breast cancer patients [22]. The gene discussed is FBXO28; the disease is neoplasm.