In another study, Jiang et al. reported decreased autophagosome formation, as well as decreased expression of the mitophagy receptor NIX and the autophagy promotor genes AMPK and ULK1, in bone marrow nucleated red blood cells from patients with high-risk MDS compared to controls and low-risk MDS patients. The gene discussed is BNIP3L; the disease is myelodysplastic syndrome.