HK2 and acute myeloid leukemia: The expression of HIF-1α and GLUT1, as well as that of two of the key enzymes controlling the glycolytic flux, namely, hexokinase 2 (HK2) and LDH, was increased in bone marrow cells from AML patients with no remission (NR), compared to healthy control individuals and patients with complete remission (CR) and partial remission (PR).