In pancreatic cancer, the lncRNA MTSS1-AS upregulated its sense gene, metastasis suppressor 1 (MTSS1), by acting as a scaffold/decoy between E3 ubiquitin-protein ligase STIP1 homology and U-box containing protein 1 (STUB1), which earmarks proteins for proteasomal degradation and the transcription regulator myeloid zinc finger 1 (MZF1). The gene discussed is MTSS1; the disease is familial pancreatic carcinoma.