BRCA1 methylated tumours are also sensitive to PARP inhibition [8], as are tumours with mutations in other genes that function in repair of double strand breaks (DSBs), including RAD51C, RAD51D, ATM and PALB2, where tumours are described as having a “BRCAness” phenotype [8,9,10]. The gene discussed is RAD51C; the disease is neoplasm.