Based on the imperative regulation of neurotrophins and their receptors on the noradrenergic system, we propose a potential peripheral molecular biomarker underlying schizophrenia, whose reduced expression of NT-3, TrkC, and NET, and the lack of molecular complexes in T cells may lead to a peripheral dysregulation of the signaling pathways and an abnormal reuptake of NE by NET. Here, NTRK3 is linked to schizophrenia.