MAPKAPK2 and neoplasm: Phinney, B.B. et al. proved that TAMs secrete the chemokines monocyte chemotactic protein-1 (MCP1) and macrophage inflammatory proteins 1α and 2α (MIP-1α and MIP-2α) via the MAPK-activated protein kinase 2 (MK2) pathway, which induces tumor cell growth and invasion in vitro [67].