Further proving that the expansion of Proteobacteria associated with low abundance of strictly anaerobes may correlate with susceptibility to infection, the results in p47phox–/– mice, a murine model of chronic granulomatous disease (CGD), showed that these mice, while unable to control the fungal growth (Figure 7A,B), in agreement with previous findings [20], showed increased abundance of Proteobacteria (Figure 7C) and reduced levels of Firmicutes (Figure 7C) and SCFAs (Figure 2B). Here, NCF1 is linked to chronic granulomatous disease.