Figure 3 summarizes the results obtained for the four CRC cell lines (HCT-116, Caco-2, HT-29 and SW620 CTRL cells), as well as for HT-29 and SW620 CTRL, KD-01 and KD-02 clones. Strikingly, one of the genes analyzed, BCL2L15, was selectively expressed only in HT-29 and SW620 CRC responder cell lines and not detectable in both HCT-116 and Caco-2 non-responders, suggesting a difference among these two groups of CRC cancer cells (Figure 3 and Supplementary Figure S1). This evidence concerns the gene BCL2L15 and cancer.