Riedl et al. were able to prove this association by caspase-3/7 cleavage studies as well as via apoptotic DNA fragmentation analysis [24], studies with PS depletion on cancer cell plasma membranes, induction of mitochondrial swelling and vesicle trafficking upon specific peptide entrance in melanoma cells upon localization to Golgi [24,64]. Here, CASP3 is linked to cancer.